Exploring the connectome: petascale volume visualization of microscopy data streams

J. Beyer, M. Hadwiger, A. Al-Awami, W.K. Jeong, N. Kasthuri, J. Lichtman, H. Pfister
IEEE Computer Graphics and Applications, 33(4), pp. 50-61, (2013)

Exploring the connectome: petascale volume visualization of microscopy data streams

Keywords

Petascale volume visualization

Abstract

​Recent advances in high-resolution microscopy let neuroscientists acquire neural-tissue volume data of extremely large sizes. However, the tremendous resolution and the high complexity of neural structures present big challenges to storage, processing, and visualization at interactive rates. A proposed system provides interactive exploration of petascale (petavoxel) volumes resulting from high-throughput electron microscopy data streams. The system can concurrently handle multiple volumes and can support the simultaneous visualization of high-resolution voxel segmentation data. Its visualization-driven design restricts most computations to a small subset of the data. It employs a multiresolution virtual-memory architecture for better scalability than previous approaches and for handling incomplete data. Researchers have employed it for a 1-teravoxel mouse cortex volume, of which several hundred axons and dendrites as well as synapses have been segmented and labeled.

Code

DOI: 10.1109/MCG.2013.55

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